My PC has been running a bit slow lately with all the things running as they used to previously when my PC was working good like antivirus and antispyware ,just needed help in order to pinpoint if the problem is indeed a virus related or something else ,posting my HJT log
PS:172.16.100.1 is my internet server add

Logfile of Trend Micro HijackThis v2.0.0 (BETA)
Scan saved at 11:03:39 PM, on 8/24/2008
Platform: Windows XP SP2 (WinNT 5.01.2600)
Boot mode: Normal

Running processes:
C:\WINDOWS\System32\smss.exe
C:\WINDOWS\system32\csrss.exe
C:\WINDOWS\system32\winlogon.exe
C:\WINDOWS\system32\services.exe
C:\WINDOWS\system32\lsass.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\svchost.exe
C:\Program Files\TGTSoft\StyleXP\StyleXPService.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\system32\svchost.exe
C:\Program Files\Lavasoft\Ad-Aware 2007\aawservice.exe
C:\WINDOWS\Explorer.EXE
C:\WINDOWS\system32\spoolsv.exe
C:\WINDOWS\system32\VTTimer.exe
C:\WINDOWS\system32\RUNDLL32.EXE
C:\Program Files\Java\jre1.6.0_05\bin\jusched.exe
C:\Program Files\ESET\ESET NOD32 Antivirus\egui.exe
C:\Program Files\Spyware Doctor\pctsTray.exe
C:\Program Files\Internet Download Manager\IDMan.exe
C:\WINDOWS\system32\ctfmon.exe
C:\PROGRA~1\Yahoo!\MESSEN~1\YAHOOM~1.EXE
C:\Program Files\Google\GoogleToolbarNotifier\GoogleToolbarNotifier.exe
C:\Program Files\eLitecore\Cyberoam Client for 24Online\CyberoamClient.exe
C:\Program Files\Adobe\Photoshop Elements 4.0\PhotoshopElementsFileAgent.exe
C:\WINDOWS\system32\drivers\CDAC11BA.EXE
C:\Program Files\ESET\ESET NOD32 Antivirus\ekrn.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\system32\nvsvc32.exe
C:\WINDOWS\system32\PnkBstrA.exe
c:\Program Files\Common Files\Protexis\License Service\PsiService_2.exe
C:\Program Files\Spyware Doctor\pctsAuxs.exe
C:\Program Files\Spyware Doctor\pctsSvc.exe
C:\WINDOWS\system32\svchost.exe
C:\WINDOWS\System32\alg.exe
C:\Program Files\Mozilla Firefox\firefox.exe
C:\WINDOWS\system32\taskmgr.exe
D:\Rameez\Softwares\JackThis.exe
C:\WINDOWS\system32\wbem\wmiprvse.exe

R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Page_URL = http://www.yahoo.com
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Default_Search_URL = http://go.microsoft.com/fwlink/?LinkId=54896
R1 - HKLM\Software\Microsoft\Internet Explorer\Main,Search Page = http://go.microsoft.com/fwlink/?LinkId=54896
R0 - HKLM\Software\Microsoft\Internet Explorer\Main,Start Page = http://www.yahoo.com
R1 - HKCU\Software\Microsoft\Internet Connection Wizard,ShellNext = http://www.eset.com/download/index.php
R1 - HKCU\Software\Microsoft\Internet Explorer\Main,Window Title = Windows Internet Explorer provided by Yahoo!
R1 - HKCU\Software\Microsoft\Windows\CurrentVersion\Internet Settings,ProxyOverride = *.local
R3 - URLSearchHook: Yahoo! Toolbar - {EF99BD32-C1FB-11D2-892F-0090271D4F88} - (no file)
O2 - BHO: IDMIEHlprObj Class - {0055C089-8582-441B-A0BF-17B458C2A3A8} - C:\Program Files\Internet Download Manager\IDMIECC.dll
O2 - BHO: HP Print Enhancer - {0347C33E-8762-4905-BF09-768834316C61} - C:\Program Files\HP\Smart Web Printing\hpswp_printenhancer.dll
O2 - BHO: HP Print Clips - {053F9267-DC04-4294-A72C-58F732D338C0} - C:\Program Files\HP\Smart Web Printing\hpswp_framework.dll
O2 - BHO: Adobe PDF Reader Link Helper - {06849E9F-C8D7-4D59-B87D-784B7D6BE0B3} - C:\Program Files\Common Files\Adobe\Acrobat\ActiveX\AcroIEHelper.dll
O2 - BHO: RealPlayer Download and Record Plugin for Internet Explorer - {3049C3E9-B461-4BC5-8870-4C09146192CA} - C:\Program Files\Real\RealPlayer\rpbrowserrecordplugin.dll
O2 - BHO: SSVHelper Class - {761497BB-D6F0-462C-B6EB-D4DAF1D92D43} - C:\Program Files\Java\jre1.6.0_05\bin\ssv.dll
O2 - BHO: (no name) - {7E853D72-626A-48EC-A868-BA8D5E23E045} - (no file)
O2 - BHO: Windows Live Sign-in Helper - {9030D464-4C02-4ABF-8ECC-5164760863C6} - C:\Program Files\Common Files\Microsoft Shared\Windows Live\WindowsLiveLogin.dll
O2 - BHO: Google Toolbar Helper - {AA58ED58-01DD-4d91-8333-CF10577473F7} - c:\program files\google\googletoolbar1.dll
O2 - BHO: Google Toolbar Notifier BHO - {AF69DE43-7D58-4638-B6FA-CE66B5AD205D} - C:\Program Files\Google\GoogleToolbarNotifier\3.0.1225.9868\swg.dll
O3 - Toolbar: &Google - {2318C2B1-4965-11d4-9B18-009027A5CD4F} - c:\program files\google\googletoolbar1.dll
O4 - HKLM\..\Run: [VTTimer] VTTimer.exe
O4 - HKLM\..\Run: [S3Trayp] S3trayp.exe
O4 - HKLM\..\Run: [NvCplDaemon] RUNDLL32.EXE C:\WINDOWS\system32\NvCpl.dll,NvStartup
O4 - HKLM\..\Run: [nwiz] nwiz.exe /install
O4 - HKLM\..\Run: [NvMediaCenter] RUNDLL32.EXE C:\WINDOWS\system32\NvMcTray.dll,NvTaskbarInit
O4 - HKLM\..\Run: [SunJavaUpdateSched] "C:\Program Files\Java\jre1.6.0_05\bin\jusched.exe"
O4 - HKLM\..\Run: [egui] "C:\Program Files\ESET\ESET NOD32 Antivirus\egui.exe" /hide /waitservice
O4 - HKLM\..\Run: [ISUSPM Startup] C:\PROGRA~1\COMMON~1\INSTAL~1\UPDATE~1\isuspm.exe -startup
O4 - HKLM\..\Run: [ISTray] "C:\Program Files\Spyware Doctor\pctsTray.exe"
O4 - HKCU\..\Run: [IDMan] C:\Program Files\Internet Download Manager\IDMan.exe /onboot
O4 - HKCU\..\Run: [ctfmon.exe] C:\WINDOWS\system32\ctfmon.exe
O4 - HKCU\..\Run: [Yahoo! Pager] "C:\PROGRA~1\Yahoo!\MESSEN~1\YAHOOM~1.EXE" -quiet
O4 - HKCU\..\Run: [swg] C:\Program Files\Google\GoogleToolbarNotifier\GoogleToolbarNotifier.exe
O4 - HKUS\S-1-5-18\..\Run: [Nokia.PCSync] "C:\Program Files\Nokia\Nokia PC Suite 6\PcSync2.exe" /NoDialog (User 'SYSTEM')
O4 - HKUS\.DEFAULT\..\Run: [Nokia.PCSync] "C:\Program Files\Nokia\Nokia PC Suite 6\PcSync2.exe" /NoDialog (User 'Default user')
O4 - Global Startup: 24Online Client.lnk = C:\Program Files\eLitecore\Cyberoam Client for 24Online\CyberoamClient.exe
O8 - Extra context menu item: Download all links with IDM - C:\Program Files\Internet Download Manager\IEGetAll.htm
O8 - Extra context menu item: Download FLV video content with IDM - C:\Program Files\Internet Download Manager\IEGetVL.htm
O8 - Extra context menu item: Download with IDM - C:\Program Files\Internet Download Manager\IEExt.htm
O8 - Extra context menu item: E&xport to Microsoft Excel - res://C:\PROGRA~1\MICROS~2\OFFICE11\EXCEL.EXE/3000
O9 - Extra button: (no name) - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_05\bin\ssv.dll
O9 - Extra 'Tools' menuitem: Sun Java Console - {08B0E5C0-4FCB-11CF-AAA5-00401C608501} - C:\Program Files\Java\jre1.6.0_05\bin\ssv.dll
O9 - Extra button: HP Clipbook - {58ECB495-38F0-49cb-A538-10282ABF65E7} - C:\Program Files\HP\Smart Web Printing\hpswp_extensions.dll
O9 - Extra button: HP Smart Select - {700259D7-1666-479a-93B1-3250410481E8} - C:\Program Files\HP\Smart Web Printing\hpswp_extensions.dll
O9 - Extra button: Research - {92780B25-18CC-41C8-B9BE-3C9C571A8263} - C:\PROGRA~1\MICROS~2\OFFICE11\REFIEBAR.DLL
O9 - Extra button: Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O9 - Extra 'Tools' menuitem: Windows Messenger - {FB5F1910-F110-11d2-BB9E-00C04F795683} - C:\Program Files\Messenger\msmsgs.exe
O16 - DPF: {30528230-99f7-4bb4-88d8-fa1d4f56a2ab} (YInstStarter Class) - C:\Program Files\Yahoo!\Common\yinsthelper.dll
O16 - DPF: {D27CDB6E-AE6D-11CF-96B8-444553540000} (Shockwave Flash Object) - http://fpdownload2.macromedia.com/get/flas...ent/swflash.cab
O17 - HKLM\System\CCS\Services\Tcpip\..\{49B18366-7682-400E-A031-5DEF6DAC649A}: NameServer = 172.16.100.1
O20 - AppInit_DLLs:
O22 - SharedTaskScheduler: Browseui preloader - {438755C2-A8BA-11D1-B96B-00A0C90312E1} - C:\WINDOWS\system32\browseui.dll
O22 - SharedTaskScheduler: Component Categories cache daemon - {8C7461EF-2B13-11d2-BE35-3078302C2030} - C:\WINDOWS\system32\browseui.dll
O23 - Service: Ad-Aware 2007 Service (aawservice) - Lavasoft - C:\Program Files\Lavasoft\Ad-Aware 2007\aawservice.exe
O23 - Service: Adobe LM Service - Adobe Systems - C:\Program Files\Common Files\Adobe Systems Shared\Service\Adobelmsvc.exe
O23 - Service: Adobe Version Cue CS2 - Adobe Systems Incorporated - C:\Program Files\Adobe\Adobe Version Cue CS2\bin\VersionCueCS2.exe
O23 - Service: Adobe Active File Monitor V4 (AdobeActiveFileMonitor4.0) - Unknown owner - C:\Program Files\Adobe\Photoshop Elements 4.0\PhotoshopElementsFileAgent.exe
O23 - Service: C-DillaCdaC11BA - Macrovision - C:\WINDOWS\system32\drivers\CDAC11BA.EXE
O23 - Service: Eset HTTP Server (EhttpSrv) - ESET - C:\Program Files\ESET\ESET NOD32 Antivirus\EHttpSrv.exe
O23 - Service: Eset Service (ekrn) - ESET - C:\Program Files\ESET\ESET NOD32 Antivirus\ekrn.exe
O23 - Service: FLEXnet Licensing Service - Macrovision Europe Ltd. - C:\Program Files\Common Files\Macrovision Shared\FLEXnet Publisher\FNPLicensingService.exe
O23 - Service: Google Updater Service (gusvc) - Google - C:\Program Files\Google\Common\Google Updater\GoogleUpdaterService.exe
O23 - Service: InstallDriver Table Manager (IDriverT) - Macrovision Corporation - C:\Program Files\Common Files\InstallShield\Driver\11\Intel 32\IDriverT.exe
O23 - Service: NVIDIA Display Driver Service (NVSvc) - NVIDIA Corporation - C:\WINDOWS\system32\nvsvc32.exe
O23 - Service: PnkBstrA - Unknown owner - C:\WINDOWS\system32\PnkBstrA.exe
O23 - Service: Protexis Licensing V2 (PSI_SVC_2) - Protexis Inc. - c:\Program Files\Common Files\Protexis\License Service\PsiService_2.exe
O23 - Service: PC Tools Auxiliary Service (sdAuxService) - PC Tools - C:\Program Files\Spyware Doctor\pctsAuxs.exe
O23 - Service: PC Tools Security Service (sdCoreService) - PC Tools - C:\Program Files\Spyware Doctor\pctsSvc.exe
O23 - Service: ServiceLayer - Nokia. - C:\Program Files\PC Connectivity Solution\ServiceLayer.exe
O23 - Service: StyleXPService - Unknown owner - C:\Program Files\TGTSoft\StyleXP\StyleXPService.exe

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End of file - 9560 bytes

There's nothing malicious showing in the log, Raptorz. Have you cleaned out all temp and temp internet files?

Install CCleaner and use it to delete all junk files, then run defrag and see if there's any improvement.

Thanks Hked
Well ill give it a try