I have motherboard drivers and display on with out any problems.
Now Spybot-S&D, Ad-Aware SE, SpywareBlaster 3.4 and latest CCleaner all sem to work fine.

Next a registry cleaner I wouldn't mind and a firewall (not so much need have hardware one mostly I want for controlling what’s outbound)
The only x64 reg cleaner I can find now is TweakNow RegCleaner Professional http://www.tweaknow.com/RegCleanerPro.html has anyone brought it/used it?
Don't say regseeker I tried it who I was test out a few other apps and it corrupted the registry so It has to be one that says its for x64 which TweakNow RegCleaner Professional is.

Anyone else had much to do with x64 ?

Have you even had time to install/uninstall tons of applications where the use of a reg cleaner might help clean things up?

Looks like you've already seen the disadvantages of running some reg cleaners. It only takes one or two missing entries to kill your setup.

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Have you even had time to install/uninstall tons of applications where the use of a reg cleaner might help clean things up?

Not yet just on the look out for a decent one.

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Looks like you've already seen the disadvantages of running some reg cleaners. It only takes one or two missing entries to kill your setup.

Yeah I have.