Better let Windows manage your virtual memory settings. Sorry, but I typed 2.5x accidentally, ideal pagefile setting is 1.5xRAM capacity.
You can safely set it beyond this limit and test it to see if it works, as you have a lot of disk space
If your computer is working fine (as you said) except for this, you can delete very huge files by using [Shift][Del] instead of [Del]. Note that files deleted by this way may not be recovered later without specialized tools.